In the presence of strong acids, THF converts to a linear polymer called poly(tetramethylene ether) glycol (PTMEG), also known as polytetramethylene oxide (PTMO)
The other main application of THF is as an industrial solvent for polyvinyl chloride (PVC) and in varnishes.THF is often used in polymer science. THF is used as a component in mobile phases for reversed-phase liquid chromatography.
THF is used as a solvent in 3D printing when using PLA plastics. It can be used to clean clogged 3D printer parts, as well as when finishing prints to remove extruder lines and add a shine to the finished product. Recently THF is used as co-solvent for lithium metal batteries, helping to stabilize the metal anode.
In the laboratory, THF is a popular solvent when its water miscibility is not an issue.
In the presence of a solid acid catalyst, THF reacts with hydrogen sulfide to give tetrahydrothiophene.










